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Creatine Gluconate is the newest type of creatine and will probably turn out to be the most effective form to hit the supplement market. Developed by Bruce Kneller exclusively for Gaspari Nutrition, this is actually the ionic salt of a creatine ion bonded to a glucose ion. The result is that you have something that gets absorbed into the system in much of the same way glucose does (easily and almost completely), mixes very well into water, tastes great and more importantly, if likely to be the most effective creatine ever made. The reason for this is as elegant as it is simple: Most of the delivery systems used to get creatine into the blood and muscle from the GI track use a 'single stage delivery system' - they work, some work very well, but they don't provide optimal or maximal delivery. For example Creatine Ethyl Ester (CEE) uses the ethyl ester to deliver the creatine into the bloodstream (and it does this very well) but when the molecule splits into ions, you are left with creatine (good) and ethyl alcohol/ethanol (not so good). There is no "afterburner" affect to push the creatine into the muscle cells faster or with more "force". The creatine "gets into the muscle cells" at less than an optimal or maximal rate. But with Creatine Gluconate, the glucose is the delivery system. It is absorbed well from the GI track into the bloodstream and when "the split" occurs, you end up with creatine and glucose (much better than alcohol) and glucose causes a nice insulin spike to help push itself, along with the creatine, into the muscle cells with "more force" and much faster. This two staged delivery system is unique among all creatines on the market.