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1. What is a transdermal and how does it work?

TRANS; meaning "across", DERMAL; meaning "the skin". Although we think of the primary purpose of the skin as a barrier to keep things out of the body, scientists have known for at least 2 centuries that certain compounds have the ability to cross the layers of the skin and obtain access to blood vessels and the general circulation.

Modern medicine has responded with the development of methods to deliver drugs transdermally for therapeutic use as an alternative to traditional routes.